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Potaba Peyronie's Treatment

There are some indications that Potaba Peyronie's treatment may help to stabilize the Peyronie's disease and reduce the plaque size. The downside, Potaba is the most expensive oral Peyronie's treatment option and can be badly tolerated by some men with the disease.

In this article, I will explain how Potaba works, the benefits of using Potaba as Peyronie's treatment, possible side effects, and references to scientific studies.

What Is Potaba?

The generic name is Potassium Aminobenzoate (also referred to as Aminobenzoate Potassium / Potassium Paraaminobenzoate) but Potaba is the most recognized brand name for it. Other well-known brand names include M2 Potassium and PABA. For ease of read, I will be using the name Potaba to represent all brands of Potassium Aminobenzoate.

Potassium Aminobenzoate is related to vitamin B. Potaba is most commonly used to treat fibrosis (thickening and scarring of connective tissue) and inflammation, hence its use for treating Peyronie's disease.

How Does Potaba Peyronie's Treatment Work?

Potaba can soften the skin and tissues when used over time and as such may help to reduce the Peyronie's plaque and stabilize the disease.

Potaba for Peyronie's disease is only available by prescription. Recommended Potaba dosage for Peyronie's patients is 12 grams per day (twenty-four 0.5 grams tablets / capsules). It is recommended to take six tablets / capsules at the time, i.e. four times a day.

What Are The Potaba Benefits?

All oral Peyronie's treatments are convenient as such, as all you have to do is to remember to swallow some tablets. In the case of Potaba, you must remember to do so four times a day.

What Are The Potaba Side Effects?

The downside is that Potaba is not well tolerated by many Peyronie's patients. Most common side effects and complaints are related with gastrointestinal upset. To prevent stomach upset, you should always take Potaba with meal or snack and make sure you drink enough liquid with it.

Other less common side effects include reduced appetite, nausea, fever and rash.

Is There Any Health Risk Involved
In Potaba Treatment For Peyronie's Disease?

Potaba is considered relatively safe medicine. An overdose is not likely to cause life-threatening symptoms. Low blood sugar is the most likely result of taking too much of Potaba.

Potaba can interfere with other medicines, including some antibiotics, so always inform your doctor of the medication you are, or recently have been taking. It is also important to inform your doctor if you have diabetes, kidney disease or chronic low blood sugar (hypeoglycemia).

You should also avoid drinking alcohol while taking Potaba, as alcohol can lower your blood sugar.

The Results Of Using Potaba For Peyronie's Disease

Potaba Peyronie's treatments may help to stabilize the disease and reduce the plaque size. Potaba has not effectively been shown to reduce the penis pain. Nor is there convincing evidence that Potaba can reduce penis curvature, i.e. preventing progression yes, reducing/correcting it no.

Scientific Support For Potaba Peyronie's Treatment

The most widely referred Potaba Peyronie's study (prospective, placebo-controlled, randomized study) indicates positive effect on the Peyronie's plaque and Potaba's ability to prevent the progression of the disease:

The results of this study indicate a significant plaque-related effect of potassium paraaminobenzoate. There was no relevant difference with regard to improvement of pre-existing penile deviation. However, under potassium paraaminobenzoate a significant protective effect on deterioration of penile curvature could be demonstrated. Potassium paraaminobenzoate appears to be useful to stabilize the disorder and prevent progression of penile curvature(PubMed - 2005)

My Personal Experience
And Opinion Of Using Potaba For Peyronie's

I do not have any personal experience of Potaba Peyronie's treatment.

However, the reported success of Potaba in reducing the plaque and stabilizing the progression of the disease is of interest to me. On the downside is the high cost, the frequent dosing requirements and how badly tolerated Potaba seems to be for some men.

First regarding the cost of Potaba compared to other oral Peyronie's treatment options. I feel you have to look at the big picture. Taking cheap drug over long periods does add up. More importantly though, taking cheap drug with no or limited affect on the disease could end up costing you more as time is of essence when fighting Peyronie's disease.

However, the high cost of Potaba is likely to affect the decision of which oral Peyronie's treatment to go for. I understand those tempted to try Potaba (if affordable to them) but there are other oral treatments, like Pentoxifylline and Carnitine, which might be as reasonable to try.

I would definitely discuss using Potaba with my doctor and I might be tempted to try it. However, as Potaba seems to work only on part of the problem, I would most likely take it in conjunction with some other Peyronie's treatment option.

Potaba Peyronie's treatment does not seem to work on the penis curvature, which in my opinion is vital to address as well as the progression of the disease and the plaque size. I would therefore consider using Potaba in conjunction with using Penis Traction Device.


Comments On This Article

  1. Charlie August, 2015

    I was treated for Peyronies in the late 70s early 80s using Potaba.  I thought it was doing nothing, but eventually it went away, with no visible traits.  I now have Dupuytren's Contracture and Leiderhose, the holy trinity of this blasted disease.  I would love to know if anyone has used Potaba to treat my current diseases. 

    Tom May, 2018

    Was treated with potaba for peyronies in late 70's. I didn't have much curvature but substantial pain.eventualy the plaque disappeared but I was never quite the same.

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This website is based on my experience of Peyronie's disease