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Tamoxifen Peyronie's Treatment

Tamoxifen Peyronie's treatment may inhibit inflammation responses in Peyronie's disease. However, there is more serious health risk involved than in any other oral Peyronie's treatment.

In this article I will explain how Tamoxifen works, the benefits of using Tamoxifen as Peyronie's disease treatment, possible side effects, and references to scientific studies.

What Is Tamoxifen?

Tamoxifen is FDA approved treatment for breast cancer.

The female hormone estrogen can promote the development of cancer in the breasts. Tamoxifen blocks the activity of estrogen and as such can prevent / stop the growth of breast cancer.

How Does Tamoxifen Work For Peyronie's Disease?

Tamoxifen is thought to inhibit inflammation responses in Peyronie's disease.

Tamoxifen for Peyronie's should always be prescribed by a doctor. The recommended dosage is 20 mg twice a day, taken with food to minimize stomach upset.

Most reputable Peyronie's specialists recommend using Tamoxifen for Peyronie's for maximum period of 3 months.

What Are The Tamoxifen Benefits?

Tamoxifen has the convenience of a tablet and is available as generic drug. As such it can be low cost oral Peyronie's treatment option.

What Are The Tamoxifen Side Effects?

Tamoxifen tends to be fairly well tolerated but if not, then the Tamoxifen side effects can be severe.

The most common Tamoxifen side effects include gastrointestinal distress and hair loss (alopecia). Men who take Tamoxifen may experience headaches, nausea / vomiting, skin rash and impotence / decrease in sexual interest.

Some Tamoxifen side effects are more serious though and can risk your overall health, i.e. vision problems, bleeding and muscle weakness.

Is There Any Health Risk Involved
In Using Tamoxifen For Peyronie's Disease?

There is an overall warning for using Tamoxifen as it may cause cancer, stroke and / or blood clots in the lungs. These conditions are serious and may be fatal.

It is therefore vital that you advice your doctor if you have ever had a stroke, heart attack or blood clot in the lungs or legs.

You also need to be aware of Tamoxifen drug interactions, especially if you are taking any blood thinning medication. Always advice your doctor about all medication you are, or have been recently taking, before starting Tamoxifen Peyronie's treatment.

The Results Of Using Tamoxifen For Peyronie's Disease

The evidence for efficacy in reducing penile curvature, penis pain and plaque size are generally considered unconvincing. However, men in the early phase of the disease may see more improvements than those with more advanced disease.

Scientific Support For Tamoxifen Peyronie's Treatment

Scientific Tamoxifen studies have not shown any convincing evidence for its effectiveness. Study that evaluated the effects of oral Tamoxifen and placebo in patients with Peyronie's disease concluded:

This study did not show significant improvement in pain, curvature or plaque size in patients with Peyronie's disease who were treated with tamoxifen compared with those treated with placebo(PubMed - 1999)

While another study showed that Acetyl-L-Carnitine notably outperformed Tamoxifen in treating Peyronie's disease. See my article on using Acetyl-L-Carnitine as oral treatment for Peyronie’s disease.

My Personal Experience
And Opinion Of Using Tamoxifen For Peyronie's

I have no personal experience of using Tamoxifen for Peyronie's disease.

The limited results and the serious health risk means I personally would not opt for Tamoxifen Peyronie's treatment. I cannot see its worth the risk involved and feel other options are more promising, e.g. the Three Approach Nonsurgical Treatments recommended by Dr. Levine.


Have you used Tamoxifen in your fight against the Peyronie's disease?

If so, please use the form below and leave your Comments, or relevant practical advice to other Peyronie's sufferers.

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Hello, I'm Birgir

This website is based on my experience of Peyronie's disease